The NEW ENGLAND JOURNAL of MEDICINE Tricia McKeever, Ph.D., Kevin Mortimer, Ph.D., Andrew Wilson, M.D., Samantha Walker, Ph.D., Christopher Brightling, Ph.D., Andrew Skeggs, B.Sc., Ian Pavord, F.Med.Sci., David Price, F.R.C.G.P., Lelia Duley, M.D., Mike Thomas, Ph.D., Lucy Bradshaw, M.Sc., Bernard Higgins, [...]